Small molecule

Results: 191



#Item
141Signal transduction / Proteins / Calcium signaling / Calmodulin / Cell signaling / IQ calmodulin-binding motif / EF hand / Ca2+/calmodulin-dependent protein kinase / Anthrax toxin / Biology / Cell biology / Protein domains

Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design Dóra K.Menyhárd1, György M. Keserű1,2and Gábor Náray-Szabó3,4* 1

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Source URL: real.mtak.hu

Language: English - Date: 2012-02-07 03:29:12
142HIV/AIDS / Cell signaling / Antiviral drug / Enzyme / HMG-CoA reductase / Small molecule / Protease inhibitor / Virus / Statin / Biology / Chemistry / Metabolism

drug-poster-handout.qxp:Layout[removed]:57 AM

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Source URL: www.pdb.org

Language: English - Date: 2014-11-07 10:59:20
143Optics / Biology / Microscopes / Fluorescence / Raman spectroscopy / Chemical imaging / Raman scattering / Single-molecule experiment / Fluorescence microscope / Chemistry / Microscopy / Spectroscopy

NIH COMMON FUND HIGH-RISK HIGH-REWARD RESEARCH SYMPOSIUM DECEMBER 15 – 17, 2014 POSTER ABSTRACTS – SESSION 1 (DEC. 15, 2014) Seeing molecular vibrations: optical imaging of small molecules for biology and medicine Aw

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Source URL: www.capconcorp.com

Language: English - Date: 2014-12-04 19:01:36
144Cerebrum / Limbic system / Neuroanatomy / Catecholamines / Neurotransmitters / Dopamine / The pleasure center / Ventral tegmental area / Nucleus accumbens / Brain / Anatomy / Biology

Alcohol and Dopamine Because alcohol is a small molecule it interacts with many neurotransmitter systems in the brain; this makes the action of alcohol in the brain very different from and much more complex than large mo

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Source URL: www.hamsnetwork.org

Language: English - Date: 2014-02-03 12:55:33
145Biosimilar / Biotechnology / Drugs / Biologic / Pharmaceutical industry / Drug safety / Food and Drug Administration / Pharmacovigilance / Belgian Association for Bioindustries / Pharmaceutical sciences / Pharmacology / Clinical research

Biosimilars Position paper Date: [removed]Unlike the more common pharmaceutical small-molecule drugs produced by a chemical process,

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Source URL: www.essenscia.be

Language: English - Date: 2013-06-20 10:32:16
146Biology / Rare diseases / Ciliopathy / Ion channels / Proteins / Autosomal dominant polycystic kidney / Autosomal recessive polycystic kidney / Polycystic kidney disease / Hsp90 inhibitors / Kidney diseases / Medicine / Health

Novel Small Molecule Lonidamine derivatives that inhibit Hsp90 and, therefore, its protein clients including CFTR, B-Raf/ERK, ErbB2, and Cdk4 Summary: Lonidimine derivates can be used to inhibit Hsp90 and, therefore, tre

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Source URL: kuic.ku.edu

Language: English - Date: 2014-02-21 14:56:52
147PTC Therapeutics / Pharmacology / Research / Pharmaceutical sciences / Ataluren / Genetic engineering

PTC Therapeutics Raises $26.6 Million In Private Placement Financing Company Developing Small-Molecule Drugs Targeting Post-Transcriptional Control Mechanisms Has Raised Over $130 Million To Date SOUTH PLAINFIELD, NJ - N

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Source URL: capital.vulcan.com

Language: English - Date: 2008-09-12 20:32:06
148Immune system / Proteins / Cell signaling / Apoptosis / Unfolded protein response / T cell / Protein S / Biology / Cell biology / Programmed cell death

Selective Small Molecule Activators of the Apoptotic Arm of the Unfolded Protein Response Summary: The invention involves the successful development of a first‐in‐class, potent, not generally cytotoxic, chemical pro

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Source URL: kuic.ku.edu

Language: English - Date: 2014-02-21 14:56:49
149Nutrition / Heparan sulfate / Posttranslational modification / Biology / Tetrasaccharide / Sulfation / Glycosaminoglycans / Chemistry / Chondroitin sulfate

Published on Web[removed]A Chondroitin Sulfate Small Molecule that Stimulates Neuronal Growth Sarah E. Tully, Ross Mabon, Cristal I. Gama, Sherry M. Tsai, Xuewei Liu, and Linda C. Hsieh-Wilson* DiVision of Chemistry

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Source URL: chemistry.caltech.edu

Language: English - Date: 2004-07-02 19:58:40
150Medicine / Phosphoenolpyruvate carboxykinase / Phosphoenolpyruvic acid / Hyperglycemia / Diabetes mellitus / Insulin / Endocrine system / Diabetes / Biology

A New Small Molecule Scaffold for the Inhibition of the Enzyme PEPCK Summary: PEPCK is an enzyme critical in the process of gluconeogenesis whose inhibition could be used to treat hyperglycemia and diabetes. Contact Info

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Source URL: kuic.ku.edu

Language: English - Date: 2014-01-30 10:28:30
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